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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7269e7e1af522e32ea4fbcde6c00fb13b058ef642a0deeca0164083d13bd3c97' 
  AND token = 'wi622gFzf5fmGAb4A2pPZKs+ZpTm3sNUzbZV9HYIdc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}