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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4e431ce7112627c625c0749d2e2547785fa66faa3608019f63c426f69a082e4' 
  AND token = 'V477x8slWeogUb29htatqZsjDfOYlFM25Q9RYQcP30I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}