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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '453e83003322f42c74b76246c9bd2ab2d46a22be9729ba4ca797ae8eaff8d652' 
  AND token = 'lJ0EMCDfTLFuXVEr1/T0Wwkb7AxqAifnjHTUxUZCxyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}