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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e8acb2afb7bf1343a97d70ba30ce5f277e70a4400a26be0c4c91bdff2f4cf52' 
  AND token = 'CvGFOBwOPTHFnwgM12lYFhlBN+mP5BipKsZ8Natko4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}