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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49da6769cfdb78c9e6c681d059a35ed76e1b63142f1b474dc807305973cca074' 
  AND token = '4CK4s+eqGQWZGO9EvwRW6CF9SEKbLSC42eoHFJqf4uA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}