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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78866ba5c51c115045865a724245d4afa96b24c2904a8e3a09bdcf79f00d8fbc' 
  AND token = 'IPalROpF4a1iHAoj0f6PH+TXX6XWsm2fUuDhg9+nfg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}