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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfb7ecd41ee196abd8b6a99ff91af6b1978c0ad8b6b9a6c38cd3acec8ff5b727' 
  AND token = 'esFt24dRlJ3OfNgyQXswTOQv1D9Ijl4iTY+L/gaRstk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}