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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec7cb20a45bc1a1e3282aaa2ad457ff5d58d64d5d943e0a943b85cace26de199' 
  AND token = 'fxTDwaD4UbgFvF3VUistYFPdNbL6+5mDkqABPuftycg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}