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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d3066f0644238fbb317a33b8e27e8266b1f32697f4b00496c000aea320dbd08' 
  AND token = 'KQTUqw6S1OWiksky/DRE3ZdWV0t1GR6Cv2TW7ygGhCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}