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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78f9a148b7ef56e8e2c56888c99d498dfe78c005f9543f5fd07f27ebc7eab0da' 
  AND token = 'wNSoFtDR000PYM0DV4/KTQQQ3MhHQ7j1LEFxmW1IwOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}