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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d8d4913e20722c59a0c77b7ee229e7ad49f18e146071a87c702e8f8653de723' 
  AND token = 'uMeg0IVfz+gEiL61UjQ2i1RD5pR4RsZzqj7/XxuduGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}