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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '543ec6a35ceaaee00b99a9f5143be2242d88deef381e7019fc7e04d638f29998' 
  AND token = 'RjxwVSBvt3zNnTgS0IBLpxtfCuQgpp7/f5YO2y+TMe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}