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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b651c53e75e1788b95dfada8ea8a280cc9db1b7c2a162a2f0aba8b3e8035e7f' 
  AND token = 'eQ3ENdj8biWF/uqI+G3/i8H2EMVuiAT5sDVMaTMXwB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}