SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecd27ed00683a059112364afc433a528e9d6402509f8b264d9f921628f0ee4f8' 
  AND token = '6orjbNYSBXr3R654wodEMbp+pk8TYofesix9f29AYP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}