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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ac15e166ee49a4759ac8489ac2ccd80bfbb22217e637f6722948565080f4c38' 
  AND token = '/ikwZVxIBuD4lDaPrGgV6awqfT4MEWoM/TjHBV2O0LM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}