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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c43b7aaec53f12aaced6c4818a80b14c4e7e42d505f229a120e7691c0c58b730' 
  AND token = '+KF6BAEQxI0ZcOkE0601bpV1EWSU6K6puTOk8ViaGUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}