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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60c29a5827f76d7603a0e2589639b53031b97080c5578a43cbc6d64f3b0bbf10' 
  AND token = '6fVgbTn84aTFBrmpivkNT6OSWQX6kHqK/GddPooGDjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}