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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b10068270b8204cd3078203e6d25b42f7744c1c236578331e4162d7db75d2e5b' 
  AND token = '3CvWtBqyLCeAo7tT12Orclsbzs/jbo36qvGs2Gl/xhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}