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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43900b68137f1e17b2f7ca7197304666e49178a986e014a2c002e2b0f7e5240a' 
  AND token = 'uK64PkVYEUNL8Zoxr0S1ue+ExAS9NlNIaFWxK8B3jOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}