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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a04d4a2ab46a2e66b8f9da58da82b0d4d0696fee1df0524fd98d2a47cb49929' 
  AND token = 'IrX6ttyn8JsCxQoo90Im5qNLqzvMsoBArGIwDeMuZHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}