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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4750954837eea3a8ab24d0f1494eeb6d0e45f61e6181a7a7af5cc39a37e127d' 
  AND token = 'VoOvWoBSYGc8aJB9KGtGONpZcaK9xCLfGOEkdQhsCCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}