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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78fafd212407fc718e69aa3acec78f561bbc04f6e7c26825f67f3d7131a776da' 
  AND token = 'AjPlGACEj7iPSKvAC+s6/ODlagolTElour/9INgL9X8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}