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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21a59a80f1e5c1366f1abb4ceb5b8cdd4ac58a6cf0fff243551c7e0525eebcd3' 
  AND token = '1KHTtBK9d+/Pc4X+y2Z38nq9UDKBZoBds6W9bLSEzqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}