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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66c5522b7bb45b2bb0e74eaf0c199361f50df697aeea4e9678df98a7fc8d2a38' 
  AND token = 'B+Mx7/zNwmx2MiPZ0wafQ4g1mukxSypOyoFkqaKiM+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}