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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2757a3b1063a52524dabde8bc25e031dbcf2433c854eab1edd42dc88d043b68c' 
  AND token = 'JHQcyQS85QYYfMneO49HSc/vuX4/fFuo22E2COk7nIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}