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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2db607412d54c8f5d4900feab96c6dde2269f4a238d66fb366962c38178d36aa' 
  AND token = 'vqh6v62Hg90oHMjU6OSP3xpfbwiIQUMSoIVN9b/NRXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}