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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c25640c3b65d00a7c18c16cb7a9c57099594d74ef6f5bcb7baada97ea0cc5dc' 
  AND token = 'Pq9r/KEZPg3E0YryOkf7W2s/gV+fSZHb0HAo27h3EwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}