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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3e9852439456dac346e330b523c150eb6703550640f2c66aa34ddb3f28f0375' 
  AND token = '9T1mOoFg1KkB3atjx7toMGWVpKvioI0FWTJNUXlZnyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}