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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42d861b3bef69f13155472e5aa5c0bd53756954b211b306d8b5f5d92fda83a43' 
  AND token = 'R9PiY2oLPoAchdGVcnfzaa245iPdpdeQC/hVY8gZ8tU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}