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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '249ea89553b9dece67dd41b6d13b61351aa0208d06c8f2b239f3ba9a8a3c3989' 
  AND token = 'k+1G3cISndRVxkwXuoXQV/FRmguxumgxxjA64CKdtLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}