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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bfcd8dc65376e0450b69a834d20e7a50333fb98a065f11c7153cf93fb1165f66' 
  AND token = 'NNw7RS93XTDjjMvwpNd+0ZqBv6XgO46Gd50naktNZes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}