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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8e02cfa1523f6d004af219b920057c73a69a1e50c4b8e3551b674caa05a9292' 
  AND token = 'wZ4r9iSf5j2rIUD8dSVf3j1k+WTffQ5PqXEydoEwdFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}