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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26c5f177499f9ec2acdce15640402334ba5188a367def913b859b0ab533334b5' 
  AND token = 'ssIA5eiLQvVpuJBFFrVbudA2VrhyYE9qf9CR/xL5tKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}