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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c10fe08e65a32e86cc35e56f4c6e0033a136edb007a05c45d0617209eb7d4b8' 
  AND token = 'CZcNnivA9d8DrWqB5PLjB2XVIoEnV6ZUwO/AVk+T0aE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}