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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3a89dbb7285d8cc5f8f57ed0845454ed23fea440286f084d108e070c278d773' 
  AND token = 'S6n1REMSSafWYI35hnxM8u026mn0+RqJaOlgKkd+OmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}