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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd818d66761ab4aed71f203b09f0a4a5174798f0b9272323747148461da9f6f76' 
  AND token = 'q4jhVdeIwLiMD+G3VddJgFiTTx1Rw81OJoeI+/Vf+Dw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}