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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '106b0d65a8f83c19bd530f192a1e91ac1dc48be35c95282f7ed115db2f27993c' 
  AND token = 'kAXraXGM9gv+duhaSHeBzUCWqaTkWczWj7Vn3fnoR6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}