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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c81a7649e91fe4c85156d6e1d470e1eff3c34f9c166fbbab376cc7979ccd144' 
  AND token = '+6wLT69gOdFMhHKG3xYUktEGe3AT01gD6vZuav3H88k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}