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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '151930d0d34a028bf2eed1df57d7b50ec5104867fa35f65e21644c42302712ec' 
  AND token = '+bOgPpHDYa4MLN8CZ0eMS3v+LHTYaLPo2mqcMUdJtV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}