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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '729b7e9651842fa14edbe0cd6c18f4fda38505f0184d078d25fc16c71e6563ab' 
  AND token = '8pmuALYYQjKnrO9pBWlV6iaREP6LmN4qv90d5LnrnVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}