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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e65aee6a7eef5f0442394d56c5b84c5820351a88611180d8022daa2559e64a7c' 
  AND token = 'NOfVP4E54vhfR1mtNXnqsuvWD4xjJIR4tOuDVjdCK58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}