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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c219b6c0f034c782007e541d16b1bf1094d78173aa7e2dd5066f9a2f0bc5aa52' 
  AND token = 'YFDzY2J0jOqtFrOqRdBtTT+8GSZ0Yp6BOSbiunZ2mHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}