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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c681b5f66d4fda00817cc5906652a23d94e71cd8a5159a48b9bf458689dd9d9' 
  AND token = '4z+i4bUq/vqtMoz0RxkzQhU3OUpRYssnt6akYN7M4c4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}