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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '257de44587a22399229bb78eb01b36d0e2e47e3172f36ef50a3c660c1f3ca672' 
  AND token = 'EWfn/6zoA0eA3971PsL7gLWWxQvGz9IQ59pPm+jWiP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}