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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e49515ec2939e64785b2368bd3d03c9364b3d3c33c80c0364b87f12f38c8f7c0' 
  AND token = 'aFnsNFkX48a2n3j0T/1tgYDgaJPfYMaGAI2keyFn8Q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}