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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88435a743707f2952fdb95c009ea873591ea63f8d71632941c76fd43c6a8fcf3' 
  AND token = 'ePHyD2M8Uj2kLDxEkXahlxXjIAKGgUjld3+Um8mRd4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}