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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afaf6f2d25a67d44eb5b1997f5924f3b25bf66a718de88d8f2e4043d080a0150' 
  AND token = 'WaE5C5exD+WuXjp6j2SbHeEMkq4U1+XJVw01Sw/oyE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}