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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bf7ff2dc214a6b39c81a9834970c72377be4984b4f4219d701b222a4db3b5b9' 
  AND token = '2EY16odl/hZxU+lm+WLPgQsVk3/RotQR/5kr2ErZq7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}