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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '221ac53fc89eb72c3d59732ee778601da3961ea86997ac2b4ecdf973b862b084' 
  AND token = '+EfyPZ0iz+ONPXod2iFa5Ir74w+Nj73I+eKK/H4Angc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}