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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f0012ab5ed11584a24506d4633eb42471d8a12cbb3a637fc77a456385a3f3d8' 
  AND token = 'mVI+djb/z766Sll8tYBgntl9ddBnA6iDRTJ8wXrf2Ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}